NDM-1 (New Delhi metallo-beta-lactamase)

http://www.medicinenet.com/ndm-1/article.htm

ndm1-superbug

NDM-1 stands for New Delhi metallo-beta-lactamase, which is an enzyme produced by certain strains of bacteria that have recently acquired the genetic ability to make this compound. The enzyme is active against other compounds that contain a chemical structure known as a beta-lactam ring. Unfortunately, many antibiotics contain this ring, including the penicillins, cephalosporins, and the carbapenems.

Emergence of Klebsiella pneumoniae Carbapenemase (KPC)-Producing Bacteria

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075864/

KPC Bacteria

Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria are a group of emerging highly drug-resistant Gram-negative bacilli causing infections associated with significant morbidity and mortality. Once confined to outbreaks in the northeastern United States (US), they have spread throughout the US and most of the world. KPCs are an important mechanism of resistance for an increasingly wide range of Gram-negative bacteria and are no longer limited to K pneumoniae.