Multiple Recurring C. Diff. Infections on the Rise

http://www.healthleadersmedia.com/quality/multiple-recurring-c-diff-infections-rise?spMailingID=11408261&spUserID=MTY3ODg4NTg1MzQ4S0&spJobID=1200396283&spReportId=MTIwMDM5NjI4MwS2#

The incidence of Clostridium difficile infections rose by 43% from 2001 to 2012, while the incidence of multiple recurring CDI rose by 189% over the same period.

The incidence of Clostridium difficile infections rose by 43% from 2001 to 2012, while the incidence of multiple recurring CDI rose by 189% over the same period.

Multiple recurring Clostridium difficile infections are becoming more common in the nation’s hospitals and researchers aren’t sure why. In an analysis of a large, nationwide health insurance database, researcher’s at the University of Pennsylvania’s Perelman School of Medicine found that the annual incidence of multiple recurring C. difficile (mrCDI) increased by almost 200% from 2001 to 2012.

During the same period the incidence of ordinary CDI increased by only about 40%. The study results were published this week in the Annals of Internal Medicine.

Related: C. Diff Infection Raises Hospital Costs by 40% per Case The reasons for the sharp rise in mrCDI incidence is unknown.

Researchers said the finding points to an increased burden on the healthcare system, including increased demand for new treatments for recurrent CDI. The most promising of these new treatments, fecal microbiota transplantation—the infusion of beneficial intestinal bacteria into patients to compete with C. difficile—has shown good results in small studies, but hasn’t yet been thoroughly evaluated. “The increasing incidence of C. difficile being treated with multiple courses of antibiotics signals rising demand for fecal microbiota transplantation in the United States,” said study senior author James D. Lewis, MD, professor of gastroenterology and senior scholar in the Center for Clinical Epidemiology and Biostatistics.

Related: Intractable C. Diff Infection Linked to Multiple Care Settings “While we know that fecal microbiota transplantation is generally safe and effective in the short term, we need to establish the long term safety of this procedure.” In their analysis of CDI trends, the researchers examined records on more than 40 million patients enrolled in private health insurance plans. Cases of CDI were considered to have multiple recurrences when doctors treated them with at least three closely spaced courses of CDI antibiotics.

Hospital floors, sinks pose deadly infection risks

http://www.fiercehealthcare.com/healthcare/studies-hospital-floors-sinks-pose-infection-risk?utm_medium=nl&utm_source=internal&mrkid=959610&mkt_tok=eyJpIjoiWkRjeU1tTTFPVEUyTjJaaCIsInQiOiJBNGU4aWlDQkpcL3l6eURqQUMyR2w3aVFtNStxVzBraUpQcTVOamQ4SVNEVUNDeXFQQ1RDWG5qdmptMjI4VWpiVTdHUDltN0ZTMG5ObWlHOWl0cXRmVEpjQ0h2bFU1NXJKM2YzaHBrcnc2VlVJVkoyTHJrQjBndGI5b3BGWmdJV1oifQ%3D%3D

hospital hallway

Hospital floors and sinks may pose infection risks, ones that could be overlooked when trying to control the spread of disease.

The floors in patient rooms may be contaminated by bacteria like methicillin-resistant Staphylococcus aureus (MRSA) or Clostridium difficile, according to a new study published in the American Journal of Infection Control. These pathogens, which can cause potentially deadly infections, can be spread when items are dropped on the floor, the researchers noted.

The research team swabbed a number of surfaces, including the floors, clothing, call-buttons and other high-touch items, in 159 rooms at five Cleveland hospitals, according to the study. The study included C. difficile-isolated rooms, and researchers found floors were often tainted by bacteria, most commonly with MRSA, C. difficile and vancomycin-resistant enterococci (VRE). The researchers also found that in 41% of these rooms, at least one high-touch object came in contact with the floor.

The study team said it hopes the results bring more attention to the infection risk posed by floors, which are not often considered in the conversation on infection control.

“Although healthcare facility floors are often heavily contaminated, limited attention has been paid to disinfection of floors because they are not frequently touched,” lead study author Abhishek Deshpande, M.D., Ph.D., an internal medicine physician for the Cleveland Clinic, said in an announcement. The results of our study suggest that floors in hospital rooms could be an underappreciated source for dissemination of pathogens and are an important area for additional research.”

Another recent study noted that hospital sinks may frequently host drug-resistant superbugs like MRSA or VRE. The research, which was published in Applied and Environmental Microbiology, set up five identical sinks in a lab that replicated sinks at the University of Virginia’s hospital in Charlottesville. The researchers then contaminated the sinks with E. coli bacteria, and though colonization began in drain pipes, it inched toward sink strainers before water spread it in the sink.

“This type of foundational research is needed to understand how these bacteria are transmitted, so that we can develop and test potential intervention strategies that can be used to prevent further spread,” Amy Mathers, M.D., an associate professor of medicine at pathology at University of Virginia, told HealthDay.

Big-name hospitals often fail to prevent C. diff infections

http://www.fiercehealthcare.com/hospitals/report-c-diff-infections-continue-to-be-a-struggle-for-big-name-medical-centers?utm_medium=nl&utm_source=internal&mrkid=959610&mkt_tok=eyJpIjoiTVdZNE9UbGtZemxtTXpBMCIsInQiOiJVS01rMXhPNVNhS1c0V2JKaE53TSthTHg0dWFnaXVtcUtXeEZlK0VqQTk3SFBNTG01aEJpVVN0aFhqRDZ5cmFGYitGUmtrZHV0K0JGMHBcL2twN2RBeUpSSk5MaW5vS0NcL25JQTk3T2FFTUhrPSJ9

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Some of the most well-known hospitals in the nation rank among the worst in preventing deadly Clostridium difficile infections, according to a new Consumer Reports analysis.

The publication analyzed C. diff infections at hospitals across the country, based on data reported to the Centers for Disease Control and Prevention between 2014 and 2015. It found well-known teaching hospitals like the Cleveland Clinic, Baylor University Medical Center in Dallas, Brigham and Women’s Hospital in Boston and Cedars-Sinai Medical Center in Los Angeles had the lowest or second-lowest ranking, indicators that these hospitals fall short against the national benchmark to control such infections.

“Teaching hospitals are supposed to be places where we identify the best practices and put them to work,” Lisa McGiffert, director of Consumer Reports‘ Safe Patient Project, said in an announcement of the findings. “But even they seem to be struggling against this infection.”

The report analyzed data from more than 3,100 U.S. hospitals and found that more than a third received a low score for C. diff infection control.

Only two large teaching hospitals, Mount Sinai Medical Center in Miami Beach, Florida and Maimonides Medical Center in Brooklyn, New York, earned top marks from Consumer Reportson controlling C. diff.

‘Superbug’ scourge spreads as U.S. fails to track rising human toll

http://www.reuters.com/investigates/special-report/usa-uncounted-surveillance/

Fifteen years after the U.S. declared drug-resistant infections to be a grave threat, the crisis is only worsening, a Reuters investigation finds, as government agencies remain unwilling or unable to impose reporting requirements on a healthcare industry that often hides the problem.

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C. Diff: Deadly Infection on the Rise in U.S. Hospitals

http://www.consumerreports.org/doctors-hospitals/c-diff-deadly-infection-on-rise-us-hospitals/

C. Diff. Image: Washing hands with soap.

Are hospitals doing all they can to prevent C. diff infections? Not yet, new study finds

http://medicalxpress.com/news/2015-04-hospitals-diff-infections.html

C Difficile Bacteria