Prosecuting the case against the COVID response

https://mailchi.mp/647832f9aa9e/the-weekly-gist-august-14-2020?e=d1e747d2d8

Bruce Plante Cartoon: Corona virus denial

This week, in her debut as running mate to presidential candidate Joe Biden, California Sen. Kamala Harris gave a preview of one of the Democratic ticket’s key arguments for the fall campaign, making a full-throated, prosecutorial case against the Trump administration’s handling of the coronavirus pandemic.

“The virus has impacted almost every country,” Harris said, “but there’s a reason it has hit America worse than any other advanced nation. It’s because of Trump’s failure to take it seriously from the start.

After receiving a briefing from public health experts on Thursday, Biden and Harris argued for a more comprehensive, aggressive national strategy to battle the virus, including major federal investment in contact tracing, a national mask mandate, and guaranteed free access to a COVID vaccine when it becomes available.

The remarks came as the US experienced the deadliest day of the summer so far, with nearly 1,500 COVID fatalities on Wednesday, and a seven-day rolling average of over 1,000 deaths per day for the last 17 days. Meanwhile, a new analysis by the New York Times, using data from the Centers for Disease Control and Prevention (CDC), indicated that the true US death toll from COVID may be as much as 35 percent higher than the reported total of 167K—a finding based on “excess deaths” above normal levels since March.

As President Trump continued to urge schools to reopen for in-person instruction nationwide, the White House released new guidance for ensuring students’ safe return to school. The guidance encouraged social distancing, frequent handwashing, better ventilation of school facilities, and the use of outdoor settings wherever possible.

Despite the President’s claim last week that children are “virtually immune” from the virus, a new analysis from the American Academy of Pediatrics and the Children’s Hospital Association showed that 97,000 children tested positive for COVID in the last two weeks of July alone, a 40 percent increase in the total number of known cases over that period.

About 340,000 children have tested positive so far, representing about 9 percent of all US cases. As schools face pressure to reopen, those numbers are likely to mount, and early-opening school districts in Georgia, Tennessee, Indiana, and Mississippi are already struggling to keep schools open amid rising cases.

Federal assistance to help schools deal with what seems like inevitable rounds of positive cases and closures is not forthcoming, however: after failing to reach a deal on another round of COVID relief, lawmakers have left Washington until September.

US coronavirus update: 5.2M cases; 167K deaths; 64.6M tests conducted.

 

 

 

U.S. records deadliest coronavirus day of the summer

https://www.axios.com/1485-us-coronavirus-death-record-5ee493cc-df91-4549-8c9d-43a5fee0bd87.html

U.S. records deadliest coronavirus day of the summer - Axios

The U.S. reported 1,485 deaths due to the coronavirus on Wednesday, COVID Tracking Project data shows.

Why it matters: It’s the highest single-day COVID-19 death toll since May 15, when the country reported 1,507 deaths. The U.S. has seen a total of 157,758 deaths from the virus.

The big picture: Georgia reported 109 deaths on Wednesday — its second triple-digit day in a row.

Go deeper: 5 states set single-day coronavirus case records last week

 

 

 

 

The two sides of America’s coronavirus response

https://www.axios.com/us-coronavirus-vaccine-testing-science-b656e905-67d1-4836-863e-c91f739cfd1e.html

The two sides of America's coronavirus response - Axios

America’s bungled political and social response to the coronavirus exists side-by-side with a record-breaking push to create a vaccine with U.S. companies and scientists at the center.

Why it matters: America’s two-sided response serves as an X-ray of the country itself — still capable of world-beating feats at the high end, but increasingly struggling with what should be the simple business of governing itself.

What’s happening: An index published last week by FP Analytics, an independent research division of Foreign Policy, ranked the U.S. 31st out of 36 countries in its assessment of government responses to COVID-19.

  • That puts it below developed countries like New Zealand and Denmark, and also lower than nations with fewer resources like Ghana, Kenya and South Africa.
  • The index cited America’s limited emergency health care spending, insufficient testing and hospital beds and limited debt relief.

By the numbers: As my Axios colleague Jonathan Swan pointed out in an interview with President Trump, the U.S. has one of the worst per-capita death rates from COVID-19, at 50.29 per 100,000 population.

Yes, but: Work on a COVID-19 vaccine is progressing astonishingly fast, with the Cambridge-based biotech company Moderna and the National Institutes of Health announcing at the end of July that they had begun Phase 3 of the clinical trial.

  • Their efforts are part of a global rush to a vaccine, and while companies in the U.K. and China are jockeying for the lead, U.S. companies and the NIH’s resources and expertise have been key to the effort.
  • Anthony Fauci has said he expects “tens of millions” of doses to be available by early 2021, a little over a year after the novel coronavirus was discovered.
  • If that turns out to be the case, “the Covid-19 vaccine could take a place alongside the Apollo missions as one of history’s greatest scientific achievements,” epidemiologist Michael Kinch recently wrote in STAT.

So which is the real American response to COVID-19? The bungled testing policies, the politically driven rush to reopen, the tragic racial divide seen in the sick and the dead? Or the warp-speed work to develop a vaccine in a year when most past efforts took decades?

Be smart: It’s both.

The bottom line: It can often feel as if there are two Americas, and not even a virus that has spread around the world seems capable of bridging that gap.

 

 

 

 

U.S. doing a lot less coronavirus testing

https://www.axios.com/newsletters/axios-vitals-32689a40-e409-4547-8468-b03dc589c082.html

The two sides of America's coronavirus response - Axios

The U.S. is cutting back on coronavirus testing. Nationally, the number of tests performed each day is about 17% lower than it was at the end of July, and testing is also declining in hard-hit states.

Why it matters: This big reduction in testing has helped clear away delays that undermined the response to the pandemic. But doing fewer tests can also undermine the response to the pandemic.

By the numbers: At the end of July, America was doing more than 800,000 tests a day. This week, it’s hovered around 715,000.

  • Even as states with particularly bad outbreaks pull back on their testing, the proportion of tests coming back positive is still high — which would normally be an indication that they need to be doing more tests.
  • In Texas, 19% of tests are coming back positive, according to Nephron Research. In Florida, the rate of positive tests is 18%, and in Nevada, 17%.

Yes, but: Experts have said reducing the demand for testing may be the best way to alleviate long delays, which made tests all but useless. And that appears to be working.

Driving the news: The Department of Health and Human Services estimated this week that nearly 90% of all tests are being completed within three days — a big improvement from turnaround times that had been stretching well over a week.

  • Quest Diagnostics says its expected turnaround time is now 2–3 days, and less for priority patients. LabCorp announced a similar turnaround time last week.

The bottom line: The U.S. is averaging 50,000 new cases a day, and that high caseload is ultimately why the demand for testing is more than the system can handle.

  • We can’t get our caseload under control without fast, widespread testing, but we can’t achieve fast, widespread testing with such a high caseload.

 

 

 

 

US has averaged over 1,000 coronavirus deaths per day for 16 straight days

https://www.cnn.com/2020/08/12/health/us-coronavirus-wednesday/index.html?utm_source=nl&utm_brand=wired&utm_mailing=WIR_Science_081220&utm_campaign=aud-dev&utm_medium=email&utm_term=WIR_Science&bxid=5db707423f92a422eaeaf234&cndid=54318659&esrc=bounceX&source=EDT_WIR_NEWSLETTER_0_SCIENCE_ZZ

CCR - Who'll Stop The Rain song lyrics music lyrics | Great song ...

Coronavirus continues to spread at high rates across the US South, Midwest and West, even as the total number of new Covid-19 cases has declined since a summer surge.

Nationally, over the last seven days, the US is averaging just under 53,000 new cases of Covid-19 per day, down 11% from the week prior.
As a result of all those cases, deaths from the virus have remained high. The seven-day average of daily coronavirus deaths was just over 1,000 on Tuesday, the 16th consecutive day the US averaged over 1,000 deaths per day.
Adjusting for population, states in the Southeast are seeing the most new cases. Georgia and Florida — states led by Republican governors who have not issued face mask requirements — have the highest per capita new cases over the last seven days, followed by Alabama and Mississippi.
On Wednesday, Florida reported more than 8,000 new cases and 212 new deaths, according to data released by the Florida Department of Health.
Covid-19 causes worse outcomes for older people, but young people are not immune. In Florida, people under 44 make up about 57% of the state’s 545,000 cases, 20% of the state’s 31,900 hospitalizations, and 3% of the state’s 8,765 deaths, according to state data.
Robert Ruiz, 31 and the father of a 3-year-old, was one of the 265 people under 44 who died from coronavirus in Florida.
His sister, Chenique Mills, told CNN he was overweight and had seasonal asthma but otherwise did not smoke or drink and had no underlying health conditions.
“This is all really sudden, unexpected,” she said. “I (saw) him on Friday. I (saw) him on Saturday. He was fine, to say that he was up, and he was walking and he was eating. He was functioning. So for him to be gone on Sunday? It’s just a lot to take in.
“This virus is so serious. It really really is. And I think people (won’t) understand until it hits home, because I would be one to say that I took it really lightly until it hit home.”
The virus’s ongoing spread around the country has frustrated plans to safely reopen schools, forced college football conferences to postpone the lucrative fall season, and caused vast medical and economic pain.
And it will continue to rattle American society until people more seriously adopt recommended public health measures: social distancingavoiding large indoor gatheringshand-washingmask-wearingrapid testing and quarantining the sick.
“We have to figure out how to deal with this as a whole country because as long as there are cases happening in any part, we still have transit, especially now we have students going back to college,” said Dr. Michael Mina, assistant professor of epidemiology at Harvard T.H. Chan School of Public Health. “Any cases anywhere really keep risk pretty high all across the entirety of the United States.”

 

 

 

‘A Smoking Gun’: Infectious Coronavirus Retrieved From Hospital Air

A Smoking Gun': Infectious Coronavirus Retrieved From Hospital Air ...

Airborne virus plays a significant role in community transmission, many experts believe. A new study fills in the missing piece: Floating virus can infect cells.

Skeptics of the notion that the coronavirus spreads through the air — including many expert advisers to the World Health Organization — have held out for one missing piece of evidence: proof that floating respiratory droplets called aerosols contain live virus, and not just fragments of genetic material.

Now a team of virologists and aerosol scientists has produced exactly that: confirmation of infectious virus in the air.

“This is what people have been clamoring for,” said Linsey Marr, an expert in airborne spread of viruses who was not involved in the work. “It’s unambiguous evidence that there is infectious virus in aerosols.”

A research team at the University of Florida succeeded in isolating live virus from aerosols collected at a distance of seven to 16 feet from patients hospitalized with Covid-19 — farther than the six feet recommended in social distancing guidelines.

The findings, posted online last week, have not yet been vetted by peer review, but have already caused something of a stir among scientists. “If this isn’t a smoking gun, then I don’t know what is,” Dr. Marr tweeted last week.

But some experts said it still was not clear that the amount of virus recovered was sufficient to cause infection.

The research was exacting. Aerosols are minute by definition, measuring only up to five micrometers across; evaporation can make them even smaller. Attempts to capture these delicate droplets usually damage the virus they contain.

“It’s very hard to sample biological material from the air and have it be viable,” said Shelly Miller, an environmental engineer at the University of Colorado Boulder who studies air quality and airborne diseases.

“We have to be clever about sampling biological material so that it is more similar to how you might inhale it.”

Previous attempts were stymied at one step or another in the process. For example, one team tried using a rotating drum to suspend aerosols, and showed that the virus remained infectious for up to three hours. But critics argued that those conditions were experimental and unrealistic.

Other scientists used gelatin filters or plastic or glass tubes to collect aerosols over time. But the force of the air shrank the aerosols and sheared the virus. Another group succeeded in isolating live virus, but did not show that the isolated virus could infect cells.

In the new study, researchers devised a sampler that uses pure water vapor to enlarge the aerosols enough that they can be collected easily from the air. Rather than leave these aerosols sitting, the equipment immediately transfers them into a liquid rich with salts, sugar and protein, which preserves the pathogen.

“I’m impressed,” said Robyn Schofield, an atmospheric chemist at Melbourne University in Australia, who measures aerosols over the ocean. “It’s a very clever measurement technique.”

As editor of the journal Atmospheric Measurement Techniques, Dr. Schofield is familiar with the options available, but said she had not seen any that could match the new one.

The researchers had previously used this method to sample air from hospital rooms. But in those attempts, other floating respiratory viruses grew faster, making it difficult to isolate the coronavirus.

This time, the team collected air samples from a room in a ward dedicated to Covid-19 patients at the University of Florida Health Shands Hospital. Neither patient in the room was subject to medical procedures known to generate aerosols, which the W.H.O. and others have contended are the primary source of airborne virus in a hospital setting.

The team used two samplers, one about seven feet from the patients and the other about 16 feet from them. The scientists were able to collect virus at both distances and then to show that the virus they had plucked from the air could infect cells in a lab dish.

The genome sequence of the isolated virus was identical to that from a swab of a newly admitted symptomatic patient in the room.

The room had six air changes per hour and was fitted with efficient filters, ultraviolet irradiation and other safety measures to inactivate the virus before the air was reintroduced into the room.

That may explain why the researchers found only 74 virus particles per liter of air, said John Lednicky, the team’s lead virologist at the University of Florida. Indoor spaces without good ventilation — such as schools — might accumulate much more airborne virus, he said.

But other experts said it was difficult to extrapolate from the findings to estimate an individual’s infection risk.

“I’m just not sure that these numbers are high enough to cause an infection in somebody,” said Angela Rasmussen, a virologist at Columbia University in New York.

“The only conclusion I can take from this paper is you can culture viable virus out of the air,” she said. “But that’s not a small thing.”

Several experts noted that the distance at which the team found virus is much farther than the six feet recommended for physical distancing.

“We know that indoors, those distance rules don’t matter anymore,” Dr. Schofield said. It takes about five minutes for small aerosols to traverse the room even in still air, she added.

The six-foot minimum is “misleading, because people think they are protected indoors and they’re really not,” she said.

That recommendation was based on the notion that “large ballistic cannonball-type droplets” were the only vehicles for the virus, Dr. Marr said. The more distance people can maintain, the better, she added.

The findings should also push people to heed precautions for airborne transmission like improved ventilation, said Seema Lakdawala, a respiratory virus expert at the University of Pittsburgh.

“We all know that this virus can transmit by all these modes, but we’re only focusing on a small subset,” Dr. Lakdawala said.

She and other experts noted one strange aspect of the new study. The team reported finding just as much viral RNA as they did infectious virus, but other methods generally found about 100-fold more genetic matter.

“When you do nasal swabs or clinical samples, there is a lot more RNA than infectious virus,” Dr. Lakdawala said.

Dr. Lednicky has received emails and phone calls from researchers worldwide asking about that finding. He said he would check his numbers again to be sure.

But ultimately, he added, the exact figures may not matter. “We can grow the virus from air — I think that should be the important take-home lesson,” he said.

 

 

 

 

Coronavirus: Some college students returning to campus are being met with liability waivers

https://finance.yahoo.com/news/colleges-students-liability-waivers-112753572.html

Schools that are choosing to reopen amid the coronavirus pandemic are attempting to protect themselves against possible legal blowback with legal liability waivers.

From universities to K-12 districts, some schools are sending forms with titles such as “Assumption of Risk” and “Waiver of Liability” to fend off any lawsuits should students contract coronavirus on campus or in the classroom.

“Institutions are basically trying to have it both ways,” Kevin McClure, associate professor of higher education at the University of North Carolina Wilmington, told Yahoo Finance. “They’re trying to say: ‘We are opening in the midst of significant risk, and at the same time we want you — as students or faculty or staff — to assume that risk and to not hold us responsible for the decisions that we’ve made.’”

‘Students’ ability to take responsibility both for themselves and each other’

Generally, the waiver forms note two things: That there is a risk of contracting the coronavirus if a student appears on campus and that the decision to come back cannot be held against the school.

“I know the challenge these circumstances present, but I also know our students’ ability to take responsibility both for themselves and each other,” Damon Sims, vice president for Student Affairs at Penn State, said in a press release. “If ever there was a time for them to do so, now is that time. We will do all we can to encourage that outcome, and we expect them to do all they can to make it so. We are in this together.”

Students returning to Penn State’s University Park campus, which usually houses more that 45,000 undergraduate students, are required to fill out the following “coronavirus compact” prior to their arrival on Penn State’s campus

This is the reality of the current situation’

Saint Anselm College in New Hampshire is another college asking its students to sign a waiver.

The liberal arts school is planning to conduct its fall semester primarily in-person, an option 30% of schools have chosen. Classes start for 2,000 students on August 19, university spokesperson Paul Pronovost told Yahoo Finance.

Aside from the usual safety measures — from reducing density in housing, classroom, and common spaces, restricting visitors, implementing distancing — the school is also going to administer two coronavirus tests on students upon their arrival: A rapid test and a fuller test. Saint Anselm is also planning to do surveillance testing throughout the semester.

Beyond social distancing, testing, and contact tracing, the university wants students and parents to “accept” the unique schooling situation.

There’s “simply no way for the College – or any College or institution, for that matter – to guarantee that our campus will not see cases of COVID-19,” Pronovost said in an email. “We believe it is important for students and families to understand and accept that this is the reality of the current situation.”

The liability waiver notes that students “forever release and waive my right to bring suit against Saint Anselm College, its Board of Trustees, officers, directors, managers, officials, agents, employees, or other representatives in connection with exposure, infection, and/or spread of COVID-19 related to taking classes, living or participating in activities on the Saint Anselm College Campus.”

Colleges fear an avalanche of lawsuits 

The possibility of lawsuits worried colleges enough to lobby Congress for protections from liability.

Nearly 80 education groups sent a letter to congressional leaders back in May, stating that reopening schools involves not just “enormous uncertainty about COVID-19-related standards of care” but also the “corresponding fears of huge transactional costs associated with defending against COVID-19 spread lawsuits.”

Rutgers Law Professor Adam Scales argued that we may see an uptick in litigation, at least “until Congress or the courts firmly signal that COVID is not going to be ‘the new asbestos,’” adding that courts will not likely impose severe liability on public entities like schools.

“Just because a student can get into court does not mean the student can win,” Michael Duff, a law professor at the University of Wyoming, told Yahoo Finance. “So even if the waiver does not ‘work,’ and the student can get into court, there is no guarantee that a lawyer would take the case because the case may be weak.”

There is also the issue of proof.

“The idea that liability — whether caused by negligence or gross negligence — is easy to prove is a myth,” Duff said. “The student would first have to prove that the college did not act ‘reasonably’ in the COVID-19 context.”

Given that the definition of acting “reasonably” would not necessarily involve a college being perfect with its coronavirus mitigation, Duff added, gross negligence would be “a very hard thing to prove.”

At the same time, Scales added, a liability waiver could not serve as a “get-out-of-jail-free card” a school taken to court in a coronavirus-related case brought by a student.

‘A stark dilemma’

At the end of the day, McClure noted, colleges need students to return to campus and pay tuition to survive as institutions of higher education.

“I do genuinely believe that many institutions and the people running them want to do what’s right and keep people healthy,” McClure said. “On the other hand, there are the financial realities of attempting to keep an organization up and running, and an organization whose revenue is often very much tied to people coming to campus.”

Schools are thus faced with “a stark dilemma,” McClure added, of either bringing students and faculty back to campus or “make significant cuts because we are not able to pay our bills.”

That said, given that students are paying a lot more today than previous generations in terms of tuition and fees, there is a sentiment that “institutions actually have a greater duty of care to their students.”

That idea is being put to the test amid the coronavirus pandemic, McClure said, and the liability waivers — which essentially abandon the “duty of care” that these institutions should take — fly in the face of this “consumerist moment” in higher education.

“Anytime that you’ve got people that are forking over large amounts of money and making a significant investment,” McClure said, “you can expect that they’re going to want a certain level of service and are going to be unhappy when a company or an organization isn’t delivering their end of the deal.”

 

 

 

 

The Health 202: Coronavirus keeps spreading. But at least we’ve learned more about it.

https://www.washingtonpost.com/politics/2020/08/11/health-202-coronavirus-keeps-spreading-least-we-learned-more-about-it/?utm_campaign=wp_the_health_202&utm_medium=email&utm_source=newsletter&wpisrc=nl_health202

Coronavirus: FI Strategy to Stop the Spread

Coronavirus infections are swelling in the United States, which hit 5 million cases over the weekend.

But so is the body of research on how the novel coronavirus spreads and affects people.

Dozens of studies have now been published in top medical journals, providing critical information to public health officials and medical professionals attempting to get a handle on the virus. More understanding of the virus is critical, as its aggressive spread around the country confounds President Trump’s efforts toward an economic rebound and threatens to keep schools and workplaces shuttered through the fall.

There’s a lot left to learn. But some of the blanks are starting to be filled in, now that researchers around the world have had six months to study it (check out The Post’s database of questions and answers about the pandemic).

Here are some things we learned about the virus over the summer — and some questions that persist:

 

Can asymptomatic people spread the virus?

Researchers are still trying to discover whether people without visible symptoms spread the virus at similar rates as those with symptoms. There’s been a considerable amount of confusion around this question, particularly after the World Health Organization appeared to suggest the virus isn’t spread asymptomatically — and then walked back its pronouncement the next day.

It seems clear that asymptomatic transmission does occur. People with no symptoms carry the same level of virus in their nose, throat and lungs as those with symptoms, according to a South Korean study of 303 people published last week in JAMA Internal Medicine.

The study was the first to distinguish between patients who didn’t develop symptoms initially and those who did develop symptoms later on — which can cause some confusion when looking at asymptomatic spread. Based on their observations, the researchers estimated that 30 percent of infected people never develop symptoms.

Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said last week he thinks the figure is closer to 40 percent.

“The good news about covid-19 is that about 40 percent of the population have no symptoms when they get infected,” Fauci said, but he added that asymptomatic people “are propagating the outbreak, which means that you’re going to infect someone, who will infect someone, who then will have a serious consequence.”

Are some people immune to the virus without ever getting it?

There is some very early, tentative evidence suggesting a segment of the world’s population may have partial protection thanks to the immune system’s “memory” T cells, which are trained to recognize specific invaders.

People may derive this protection from standard childhood vaccinations or from previous infections by other coronaviruses, such as those that cause the common cold, my colleague Ariana Eunjung Cha reported.

“This might potentially explain why some people seem to fend off the virus and may be less susceptible to becoming severely ill,” National Institutes of Health Director Francis Collins remarked in a blog post last week.

“On a population level, such findings, if validated, could be far-reaching,” Ariana wrote. “ … In communities in Boston, Barcelona, Wuhan and other major cities, the proportion of people estimated to have antibodies and therefore presumably be immune has mostly been in the single digits. But if others had partial protection from T cells, that would raise a community’s immunity level much higher.”

 

How many untested Americans have already had the virus?

The head of the Centers for Disease Control and Prevention estimated in June that there were roughly 10 times more coronavirus infections in the United States than had been confirmed through testing.

There were just 2.4 million confirmed cases when CDC Director Robert Redfield made that estimate — which, if accurate, would have translated to 24 million cases at the time. Confirmed cases have since doubled, to more than 5 million — meaning the virus may have swept through tens of millions of people.

Redfield based his estimate on the results of antibody tests, which examine a person’s blood for indicators that the body fought off an infection, Lena H. Sun and Joel Achenbach wrote.

 

How does the virus travel?

Scientists initially thought the virus easily spread on surfaces, similar to how other viruses operate. That’s why much of the initial public health advice centered around hand-washing and disinfecting surfaces.

Now public health experts think SARS-CoV-2 is primarily spread through person-to-person contact.

In May, the CDC updated guidance on its “How COVID-19 Spreads” website to say that “the virus spreads easily between people.” The agency also acknowledged the virus may spread other ways, such as through touching contaminated objects or surfaces, but clarified “this is not thought to be the main way the virus spreads.”

“The virus travels through the droplets a person produces when talking or coughing,” Ben Guarino and Joel wrote. “An individual does not need to feel sick or show symptoms to spread the submicroscopic virus. Close contact means within about six feet, the distance at which a sneeze flings heavy droplets. Example after example have shown the microbe’s affinity for density. The virus has spread easily in nursing homes, prisons, cruise ships and meatpacking plants — places where many people are living or working in proximity.”

 

Do children spread it?

Children only rarely get seriously ill or die of covid-19, the disease the virus causes; data on hospitalizations and deaths make that clear. But whether — and to what extent — they can spread the virus to others asymptomatically is still murky.

Studies are also conflicting on whether the age of children affects their likelihood of spreading the virus. One study conducted at a Chicago hospital found children younger than 5 with mild to moderate cases of covid-19 had much higher levels of virus in their noses than older children and adults — suggesting they could be more infectious, Ariana, Haisten Willis and Chelsea Janes reported.

But a study out of South Korea examining household transmission seemed to reach an opposite conclusion. It found children under age 10 did not appear to pass on the virus readily, while those between 10 and 19 appeared to transmit the virus almost as much as adults did, my colleagues wrote.

 

Which organs does Covid-19 attack?

The lungs appear most susceptible to the virus. Researchers have also found the pathogen in parts of the brain, kidneys, liver, gastrointestinal tract, spleen and in the endothelial cells that line blood vessels, along with widespread clotting in many organsAriana and Lenny Bernstein reported.

But researchers have been surprised to discover little inflammation on the brain, despite previous reports about neurological symptoms related to the coronavirus. The same goes for the heart. While physicians warned for months about a cardiac complication they suspected was myocarditis, autopsy investigators found no evidence of the condition.

 

Dr. Anthony Fauci says chance of coronavirus vaccine being highly effective is ‘not great’

https://www.cnbc.com/amp/2020/08/07/coronavirus-vaccine-dr-fauci-says-chances-of-it-being-highly-effective-is-not-great.html?utm_source=&utm_medium=email&utm_campaign=32192

KEY POINTS
  • White House coronavirus advisor Dr. Anthony Fauci that the chances of scientists creating a highly effective vaccine — one that provides 98% or more guaranteed protection — for the virus are slim.
  • Scientists are hoping for a coronavirus vaccine that is at least 75% effective, but 50% or 60% effective would be acceptable, too, he said.
  • The FDA has said it would authorize a coronavirus vaccine so long as it is safe and at least 50% effective.

White House coronavirus advisor Dr. Anthony Fauci said Friday that the chances of scientists creating a highly effective vaccine — one that provides 98% or more guaranteed protection — for the virus are slim.

Scientists are hoping for a coronavirus vaccine that is at least 75% effective, but 50% or 60% effective would be acceptable, too, Fauci, director of the National Institute of Allergy and Infectious Diseases, said during a Q&A with the Brown University School of Public Health. “The chances of it being 98% effective is not great, which means you must never abandon the public health approach.”

“You’ve got to think of the vaccine as a tool to be able to get the pandemic to no longer be a pandemic, but to be something that’s well controlled,” he said.

The Food and Drug Administration has said it would authorize a coronavirus vaccine so long as it is safe and at least 50% effective. Dr. Stephen Hahn, the FDA’s commissioner, said last month that the vaccine or vaccines that end up getting authorized will prove to be more than 50% effective, but it’s possible the U.S. could end up with a vaccine that, on average, reduces a person’s risk of a Covid-19 infection by just 50%.

“We really felt strongly that that had to be the floor,” Hahn said on July 30, adding that it’s “been batted around among medical groups.”

“But for the most part, I think, infectious disease experts have agreed that that’s a reasonable floor, of course hoping that the actual effectiveness will be higher.”

A 50% effective vaccine would be roughly on par with those for influenza, but below the effectiveness of one dose of a measles vaccination, which is about 93% effective, according to the Centers for Disease Control and Prevention.

Public health officials and scientists expect to know whether at least one of the numerous potential Covid-19 vaccines in development worldwide is safe and effective by the end of December or early next year, though there is never a guarantee. Drug companies Pfizer and Moderna both began late-stage trials for their potential vaccines last week and both expect to enroll about 30,000 participants.

Fauci has previously said he worries about the “durability” of a coronavirus vaccine, saying if Covid-19 acts like other coronaviruses, it may not provide long-term protection.

Health officials say there is no returning to “normal” until there is a vaccine. Fauci’s comment came a day after the World Health Organization cautioned about the development of vaccines, reiterating that there may never be a “silver bullet” for the virus, which continues to rapidly spread worldwide. The phase three trials underway do not necessarily mean that a vaccine is almost ready to be deployed to the public, the agency said.

“Phase three doesn’t mean nearly there,” Mike Ryan, executive director of the WHO’s emergencies health program, said during a virtual panel discussion with “NBC Nightly News” Anchor Lester Holt hosted by the Aspen Security Forum. “Phase three means this is the first time this vaccine has been put into the general population into otherwise healthy individuals to see if the vaccine will protect them against natural infection.”

While there is hope scientists will find a safe and effective vaccine, there is never a guarantee, WHO Director-General Tedros Adhanom Ghebreyesus said.

“We cannot say we have vaccines. We may or may not,” he said.

On Friday, Fauci reiterated that he is “cautiously optimistic” scientists will find a safe and effective vaccine. He also reiterated that the coronavirus may never be eliminated, but world leaders can work together to bring the virus down to “low levels.”

Some of Fauci’s comments have been at odds with President Donald Trump, who has repeatedly said the virus would “disappear.”

Trump, who is seeking reelection, said Thursday that it’s possible the United States could have a safe and effective vaccine for the coronavirus before the upcoming presidential election on Nov. 3.

 

 

 

 

 

97,000 children reportedly test positive for coronavirus in two weeks as schools gear up for instruction

https://www.cbsnews.com/news/covid-19-kids-school-children-positive-tests-coronavirus-reopening/?utm_source=nl&utm_brand=wired&utm_mailing=WIR_Science_081020&utm_campaign=aud-dev&utm_medium=email&utm_term=WIR_Science&bxid=5db707423f92a422eaeaf234&cndid=&esrc=bounceX&source=EDT_WIR_NEWSLETTER_0_SCIENCE_ZZ

97,000 children reportedly test positive for coronavirus in two ...

Nearly 100,000 children tested positive for the coronavirus in the last two weeks of July, a new report from the American Academy of Pediatrics finds. Just over 97,000 children tested positive for the coronavirus from July 16 to July 30, according to the association.

Out of almost 5 million reported COVID-19 cases in the U.S., CBS News’ Michael George reports that the group found that more than 338,000 were children.

Vanderbilt University’s Dr. Tina Hartert hopes increased testing of children will help determine what role they play in transmission, as school districts around the country return to some form of school. She is leading a government-funded study that saw DIY testing kits sent to some 2,000 families.

“The kits are shipped to the families, they are taught how to collect these samples, and then the samples are sent back by the families to a central repository,” she said.

In New York City, home to the nation’s largest school district, Mayor Bill de Blasio announced a return to in-person schooling in the fall and pledged officials “have worked incessantly to get this right.”

“They’ve looked at examples from all over the world of what will keep the school community safe, and they’ve made a series of choices of how to do things from the health and safety lens first, while also making sure we can educate our kids,” he said in a Friday press conference.

De Blasio gave parents until Friday night to register students for in-person instruction, remote learning or a hybrid.

More than 25 children died of the coronavirus in July alone. Pressure to get kids back into the classroom has left superintendents in more than 13,000 different school districts across the country to figure out how to keep children safe amid a myriad of public health advisories, and handle learning differences.

Niles, Michigan Superintendent Dan Applegate is hoping Plexiglas could be a solution for children with speech impediments to be able to participate in class.

He demonstrated by speaking behind a transparent slate at a press conference.

“As I’m sitting here and I can articulate,” Applegate said. “The student on the other side will be wearing a mask. Then I can put my mask on, and that student can drop their mask and articulate as well.”

Indiana’s Lawrence Township is cleaning school buses with a hospital-grade disinfectant spray for students still needing rides to school.

“You’re going to see a very clean and disinfected bus,” Transportation Director Matt Miles said. “We actually have fogging machines.”

However, they are not expecting many students to get on the bus — 35% of children in the area are expected to learn remotely, while other school districts in the U.S. will not open at all.