Doctors keep discovering new ways the coronavirus attacks the body

https://www.washingtonpost.com/health/2020/05/10/coronavirus-attacks-body-symptoms/?arc404=true&utm_campaign=29774&utm_medium=email&utm_source=

Coronavirus Causes Damage to Organs Other Than the Lungs, Doctors ...

Damage to the kidneys, heart, brain — even ‘covid toes’ — prompts reassessment of the disease and how to treat it

Deborah Coughlin was neither short of breath nor coughing. In those first days after she became infected by the novel coronavirus, her fever never spiked above 100 degrees. It was vomiting and diarrhea that brought her to a Hartford, Conn., emergency room on May 1.

“You would have thought it was a stomach virus,” said her daughter, Catherina Coleman. “She was talking and walking and completely coherent.”

But even as Coughlin, 67, chatted with her daughters on her cellphone, the oxygen level in her blood dropped so low that most patients would be near death. She is on a ventilator and in critical condition at St. Francis Hospital, one more patient with a strange constellation of symptoms that physicians are racing to recognize, explain and treat.

“At the beginning, we didn’t know what we were dealing with,” said Valentin Fuster, physician-in-chief at Mount Sinai Hospital in New York City, the epicenter of the U.S. outbreak. “We were seeing patients dying in front of us. It was all of a sudden, you’re in a different ballgame, and you don’t know why.”

Today, there is widespread recognition the novel coronavirus is far more unpredictable than a simple respiratory virus. Often it attacks the lungs, but it can also strike anywhere from the brain to the toes. Many doctors are focused on treating the inflammatory reactions it triggers and its capacity to cause blood clots, even as they struggle to help patients breathe.

Learning about a new disease on the fly, with more than 78,000 U.S. deaths attributed to the pandemic, they have little solid research to guide them. The World Health Organization’s database already lists more than 14,600 papers on covid-19. Even the world’s premier public health agencies, including the Centers for Disease Control and Prevention, have constantly altered their advice to keep pace with new developments.

“We don’t know why there are so many disease presentations,” said Angela Rasmussen, a virologist at the Center for Infection and Immunity at Columbia University’s Mailman School of Public Health. “Bottom line, this is just so new that there’s a lot we don’t know.”

More than four months of clinical experience across Asia, Europe and North America has shown the pathogen does much more than invade the lungs. “No one was expecting a disease that would not fit the pattern of pneumonia and respiratory illness,” said David Reich, a cardiac anesthesiologist and president of Mount Sinai Hospital in New York City.

It attacks the heart, weakening its muscles and disrupting its critical rhythm. It savages kidneys so badly some hospitals have run short of dialysis equipment. It crawls along the nervous system, destroying taste and smell and occasionally reaching the brain. It creates blood clots that can kill with sudden efficiency and inflames blood vessels throughout the body.

It can begin with a few symptoms or none at all, then days later, squeeze the air out of the lungs without warning. It picks on the elderlypeople weakened by previous disease, and, disproportionately, the obese. It harms men more than women, but there are also signs it complicates pregnancies.

 

 

CommonSpirit came up with a new plan to restart elective procedures. Here’s what it says

https://www.fiercehealthcare.com/hospitals-health-systems/commonspirit-gives-tookit-to-hospitals-how-to-restart-elective-surgical?mkt_tok=eyJpIjoiWldSbVlqVTFPV0l4T1dGaSIsInQiOiIwSWp6WDBDRk9GK2U5T1hkYnpsRzRleSsyQlhFb1NrR1BpbHBwZFVHSlBNOVc4cjhuQVRBZUIzRnZVQVA1UFV0ekVoUWJnZDVLeDNoQitqSmJ2c0ZpbXBcL3lLbVQ0RGlKRXlzVzNSbkthaUpUV0twQ2Z4emFGaTViemFcL1N6WTZrIn0%3D&mrkid=959610

CommonSpirit came up with a new plan to restart elective ...

Like a lot of major health systems, CommonSpirit Health is making strides to reopen elective procedures canceled due to COVID-19.

Some facilities have already resumed some surgical procedures, and others are going to start scheduling such procedures as soon as Monday.

To get started, officials say, the health system giant recently created a toolkit that they sent to its 137 hospitals that stretch across more than 20 states outlining testing, screening and supply protocols. CommonSpirit’s toolkit builds on a framework put out in recent weeks by the American Hospital Association, the American College of Surgeons and other provider groups.

A key message: Hospitals must also make sure to keep one eye on the virus and its ongoing spread in the community on a daily basis and be ready to respond accordingly. CommonSpirit says that facilities need to coordinate with local and state authorities.

“The virus isn’t going away because we reopened,” Barbara Pelletreau, senior vice president for patient safety at CommonSpirit, told FierceHealthcare.

Here’s a look at what else the health system’s new toolkit advises:

1. Assess: The toolkit offers five phases of surgical care, Pelletreau said. In the first phase, a facility must look at how to reassess the health status of patients since the cancellation of their procedure, she said.

Hospitals must adhere to the Centers for Medicare & Medicaid Services’ requirement that there is a physical examination and history of a patient within 30 days of any procedure. “This will verify if there has been no significant interim change in patient’s health status,” the toolkit said.

Hospitals can rely on telehealth for part of this evaluation.

Testing is also a critical part of the restart. Facilities should test patients before surgical procedures and tell patients to remain at home before the results come in to limit any new potential exposure.

A hospital must also create a process to determine next steps if patient testing is not available or results haven’t come back in time for the surgery.

2. Designate leadership and coordinate: As they prepare to get going again, facilities should establish a prioritization policy committee that has members from surgery, anesthesia and nursing.

The committee should examine which types of procedures should get priority to resume.

3. Ensure they have enough PPE: They also need to make sure they have enough personal protective equipment (PPE) to handle not just any new procedures but also another wave of COVID-19 cases.

For instance, one part of the toolkit recommends a facility to have a minimum of four days of PPE on hand and projection of new inventory arriving for the next two weeks.

As facilities ramp up, they must ensure they have enough primary and adjunct personnel. A hospital must also put out guidelines for who is present during intubation and extubation of the patient and how to use PPE.

Communication

However, a key element is harder to address: confidence among patients.

“In the end, you can have all the clinical facts. But it is, ‘How do you feel about your safety?’” Pelletreau said. “How do you feel about going to the grocery store or a hospital that delivers amazing medical care?”

Pelletreau said that CommonSpirit is now also working on messaging to its own employees and to the community to assure patients it is safe to return to the hospital for needed medical care. That includes several communication resources to show examples of the work it is doing, from ramped-up testing to more stringent cleaning protocols, to ensure surgical procedures can be performed safely.

“Consider a proactive approach to communicating with staff, patients, physicians and the community,” the toolkit said. “Recognize the significant interest and questions from our key audiences.”

 

 

 

 

Cartoon – Learning Online

Coronavirus socialism: Political Cartoons – Redlands Daily Facts

Cartoon – Current State of the Union

This Week's Cartoons: Coronavirus, Social Media, and Social ...

Cartoon – The Coronavirus War

Coronavirus first responders now the frontline in two wars: Darcy ...

Minneapolis Fed president: ‘The worst is yet to come on the job front’

https://thehill.com/homenews/sunday-talk-shows/497006-minneapolis-fed-president-the-worst-is-yet-to-come-on-the-job?rnd=1589121753

Minneapolis Fed president: 'The worst is yet to come on the job ...

The president of the Federal Reserve Bank of Minneapolis said Sunday that the “worst is yet to come” after a record of 20 million people lost their jobs amid furloughs and layoffs sparked by the coronavirus pandemic in April. 

“I mean the worst is yet to come on the job front, unfortunately,” Neel Kashkari said on ABC’s “This Week.”

“We may be in an environment of gradual relaxing and then having to clamp back down again around the country as the virus continues to spread,” he added. “To solve the economy, we must solve the virus. Let’s never lose sight of that fact.”

Kashkari also contradicted White House economic adviser Larry Kudlow’s prediction for a financially strong half of 2020 and full 2021 when ABC’s George Stephanopoulos asked if that was realistic.

“You know, I wish it were,” he responded. “What I’ve learned in the last few months, unfortunately, this is more likely to be a slow, more gradual recovery.”

The Minneapolis Fed president said a “robust economy” would require a breakthrough in vaccines, testing and therapies. 

“I don’t know when we’re going to have that confidence,” he said, adding, “and ultimately, the American people are going to decide how long the shutdown is.”

The Department of Labor reported last week that the unemployment rate had reached 14.7 percent, which is the highest since the U.S. began tracking in 1948. More than 33 million people have applied for unemployment claims since mid-March. 

Speaking earlier Sunday on “This Week,” Kudlow acknowledged that “very difficult” unemployment numbers could likely be reported in May. But he added that there is a “glimmer of hope” within the unemployment data, with 80 percent of the claims involving those who were furloughed or going through temporary layoffs. 

 

 

 

 

Infectious disease expert: ‘We are going to see a growth in cases’ in coming weeks

https://thehill.com/homenews/sunday-talk-shows/497011-infectious-disease-expert-we-are-going-to-see-a-growth-in-cases-in?rnd=1589123649

Infectious disease expert: 'We are going to see a growth in cases ...

Columbia University infectious diseases expert Jeffrey Shaman predicted Sunday that the U.S. will see a growth in coronavirus cases in coming weeks as some states loosen restrictions.

Shaman said on NBC’s “Meet the Press” that Trump administration officials have not taken full advantage of the past eight weeks of near-total lockdowns, saying that the period would have “benefitted enormously from consistent messaging” from the White House.

“We do need to start picking ourselves up where we are” he said, pointing to countries that appear to have successfully contained the spread of the virus, such as South Korea, Germany and New Zealand.

“They did this because they tested so aggressively and they used contact tracing and they were able to quarantine people who were becoming infectious,” he said.  “Once you’ve done that, then you’re in this position of strength where reopening the economy is not going to lead necessarily to the rebound in cases that I’m expecting, given this patchwork response that we have right now and the reopenings taking place in some states.”

“What I think we’re probably going to see over coming weeks, probably towards the end of the month, is we’re just going to start to see a growth in cases,” he added. “It’s not going to happen over the next week or two, it’s going to come in with a lag. That built-in delay means any changes we do to social distancing because of reopening, we’re not going to realize for a couple of weeks that we’re already into some period of growth.”

Multiple states have moved to reopen portions of their economy shuttered by state-at-home orders imposed to prevent the spread of coronavirus.

The Labor Department reported last week that a record 20 million Americans lost their jobs in April amid the pandemic.

 

 

 

White House adviser says unemployment may climb to 20 percent

https://thehill.com/homenews/administration/497003-white-house-advisor-says-unemployment-may-climb-to-20-percent?rnd=1589120557

White House economic adviser expects unemployment rate to climb ...

White House adviser Kevin Hassett said Sunday the U.S. unemployment rate could reach 20 percent in May. 

“I think just looking at the flow of initial claims, it looks like we’re probably going to get close to 20 percent in the next report,” Hassett said on CNN’s “State of the Union.”

He made similar comments on CBS’s “Face the Nation,” saying the low point could reach 20 percent around May or June.

Hassett said on CNN the unemployment rates depend on whether the virus “has really abated” and if economies are “really going again.” 

“I would guess middle of summer is when we’re going to start to go into the transition phase,” he said, adding that he hopes there will be “very strong” growth in the third and fourth quarters.

The unemployment in April rate rose to 14.7 percent from 4.4 percent in March, according to the latest jobs report released by the Bureau of Labor Statistics on Friday. 

The U.S. lost 20.5 million jobs in April amid the coronavirus pandemic, breaking the record for the largest one-month increase in the unemployment rate.

 

 

 

States build contact tracing armies to crush coronavirus

States build contact tracing armies to crush coronavirus

Coronavirus: Why are there doubts over contact-tracing apps? - BBC ...

State governments are building armies of contact tracers in a new phase of the battle against the coronavirus pandemic, returning to a fundamental practice in public health that can at once wrestle the virus under control and put hundreds of thousands of newly jobless people back to work.

California is already conducting contact tracing in 22 counties, and it eventually plans to field a force of 10,000 state employees, who will be given basic training by University of California health experts.

Massachusetts and Ohio have partnered with Partners in Health, a global health nonprofit originally established to support programs in Haiti, to field teams of contact tracers. Maryland will partner with the University of Chicago and NORC, formerly the National Opinion Research Center, to quadruple its contact tracing capacity.

Washington, West Virginia, Iowa, North Dakota and Rhode Island are using their National Guards to trace contacts of those who have been infected with the coronavirus. In Kansas, 400 people have volunteered to trace contacts; in Utah, 1,200 state employees have raised their hands.

Contact tracing is a pillar of basic public health, a critical element in battling infectious disease around the globe. The goal is to identify those who have been infected with a virus and those with whom the infected person has come into contact. 

If those contacts then come down with the virus, they can be quickly isolated so they do not spread it further. They can also be treated, making it less likely they develop the most severe symptoms.

The practice works even in areas where health systems are thin at best and nonexistent at worst.

Tracking down those who had the Ebola virus in Guinea, Liberia and Sierra Leone, three of the poorest nations on Earth, was critical to ending the world’s largest outbreak of the deadly hemorrhagic fever in 2015. World Health Organization trackers and health officials in Congo have tracked as many as 25,000 people at a time during an Ebola outbreak that is still simmering in an eastern province, even as they face the threat of what is an almost active war zone.

“Our ability to suppress transmission relates to our ability to detect the virus,” Maria Van Kerkhove, the American who leads the World Health Organization’s technical team studying the coronavirus, told reporters last week.

The focus on contact tracing comes as public health experts warn that the coronavirus will not end as a threat to humankind until so many people have become infected that the virus has nowhere else to turn — a terrifying prospect that conjures images of overwhelmed health systems and death on a mass scale — or until scientists develop and distribute an effective vaccine to billions of people across the globe.

There are more than 100 vaccines in some stage of testing, though determining their effectiveness is still months away, and production at a mass scale is months beyond that. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases and the country’s most well-known infectious disease expert, has estimated that a vaccine could be as close as 18 months away, though he has acknowledged that would blow the old record for speedy development out of the water.

“We have to fundamentally do everything possible to get a safe and effective vaccine as quickly as possible. At the same time, we have to assume that it’s not around the corner,” said Tom Frieden, former director of the Centers for Disease Control and Prevention who now runs Resolve to Save Lives, a global health nonprofit.

In the meantime, the federal government has largely left it up to the states to build their contact tracing capacity. 

Sen. Elizabeth Warren (D-Mass.) and Rep. Andy Levin (D-Mich.) have proposed adding a massive nationwide federal contact tracing program to the next round of coronavirus-related relief funding. In a nod to the New Deal-style scale such a program would require, they call the program the Coronavirus Containment Corps.

“Establishing a nationwide contact tracing program is the only way we can truly know the progress we’ve made in containing the virus, and how far we have left to go before we can transition back to normal life,” Levin said in a statement.

But contact tracing can work only if the number of new cases the United States confirms every day begins to bend down to a manageable number. The number of cases confirmed in the United States has grown by at least 25,000 on all but two of the first eight days of May.

And tracing will become an effective tool only when those who are conducting the tracing have the ability to test people broadly and to get the results of those tests back quickly. The Food and Drug Administration said Friday it had approved both the first diagnostic test that could be conducted using home-collected saliva samples and the first antigen test, a type of test that delivers results much faster than others on the market.

The lack of available tests at the earliest stages of the coronavirus outbreak has hidden the true extent of the virus’s spread around the United States. While some countries have the capacity to test huge percentages of their population on a given day, the United States is still testing only about 250,000 people per day, a level far short of the capacity necessary to conduct widespread contact tracing.

“Right from the start there has been a tremendous undercounting of cases, and that had to do with our now infamous slow testing rollout,” said Paul Sax, clinical director of the division of infectious diseases at Brigham and Women’s Hospital in Boston. 

President Trump has touted the raw number of tests performed — he rightly claims that the United States conducts more tests on a given day than any other country. But on a per capita basis, the United States is testing fewer of its residents than countries such as the United Kingdom, Italy and Estonia.

Until that changes, public health experts worry the United States will be stuck at a dangerous plateau.

“We’re doing deeply inadequate testing and functionally no tracing,” said Jeremy Konyndyk, a former head of the Office of Foreign Disaster Assistance at the U.S. Agency for International Development and now a senior fellow at the Center for Global Development. “We’re not going to half-ass our way out of a pandemic, and that’s where we are, and that’s why we’re stuck.”

 

 

 

 

Melinda Gates: US coronavirus response ‘lacking leadership at the federal level’

https://finance.yahoo.com/news/us-coronavirus-response-lacks-leadership-at-the-federal-level-melinda-gates-151610533.html

Melinda Gates: US coronavirus response “lacks leadership at the ...

Philanthropist Melinda Gates on Thursday sharply criticized the U.S. response to the coronavirus outbreak, telling Yahoo Finance that the country is “lacking leadership at the federal level” and as a result has endured unnecessary deaths and economic pain.

“It’s highly distressing and disappointing,” says Gates, co-chair of the Bill and Melinda Gates Foundation, which she said has donated $300 million to organizations involved in the coronavirus response.

“To have 50 state-grown solutions is inefficient, it makes no sense, and it’s costing people their lives,” she adds.

President Donald Trump said on Tuesday “there’ll be more death” as states lift stay-at-home measures but has urged a path toward reopening the economy in order to blunt job loss and other damaging effects caused by the mandates.

The Trump administration has drawn criticism for what some consider a failure to adequately address the coronavirus outbreak in its early stages. Trump has repeatedly said “nobody” could have foreseen the pandemic though he reportedly received dire warnings as early as February.

“The lack of action is really causing harm and hurt unnecessarily in this country,” Gates says. “I’m incredibly disappointed to see that.”

The White House recently declined to take up guidelines written by the Centers for Disease Control and Prevention for how schools, restaurants, and other institutions can safely reopen, the Associated Press reported on Thursday.

The Trump administration did release a set of conditions for coronavirus containment that it recommends states meet before they reopen, including a 14-day downward trajectory in new cases or positive test rates. However, many states that remain short of that benchmark have started to reopen or will do it soon, among them Kentucky, Ohio, and Utah, the AP reported on Thursday.

On Friday, the monthly jobs report showed the U.S. economy cut 20.5 million payrolls in April, and the unemployment rate jumped to 14.7%.

The severity of economic pain is a direct result of inaction from the federal government, Gates said.

“It is impacting families now, because if we had a good testing and tracing system like Germany has, we would have started to reopen slowly more places in the economy, people wouldn’t be struggling so much to put a meal on their table,” says Gates, who released a book last year entitled “The Moment of Lift: How Empowering Women Changes the World.”

‘Difficult tension’ faced by parents at home

She said the U.S. must bolster its benefits for paid sick, medical, and family leave in order to mitigate some of the economic pain and reopen the economy, since some workers will return to their jobs while others will need to remain home to care for sick family members or children educated remotely.

Speaking with Yahoo Finance, she called on Congress to improve the paid sick and family leave expansion passed in March, which excluded many companies from the benefits requirements.

“Congress made a first step that is in one of the stimulus packages, they really did put in sick days and paid leave,” she says. “The problem is, it doesn’t go far enough.”

Moreover, she advocated for a nationwide paid medical and family leave plan — a proposal backed in part by both parties, though they differ sharply on the details.

The Republican-controlled Senate and Democrat-controlled House remain divided over an additional stimulus measure, while President Donald Trump has sought likely-polarizing tax cuts to be included in the bill, the New York Times reported on Wednesday.

Nevertheless, Gates said she is optimistic that Congress will enact paid medical and family leave.

“Congress is hearing about this difficult tension moms and dads — but particularly moms — are facing at home,” she says.